Bench Top Laboratory Unit for Extruding Small Quanitites of Pharmaceutical Compounds

The Caleva Model 20 Extruder is a benchtop screen extruder with a lot of extra capabilities. 

A laboratory bench top screen (sometimes referred to as a "basket type") extruder designed for pharmaceutical R&D process development work in the laboratory. It is designed and built so that it will replicate production extrusion on the laboratory bench top. Extruder screens are identical with production machines and scale up problems can be minimized.

The unique Caleva system of roller extruders is designed to impart very little work to the product as it is processed. This reduces problems caused by overheating or drying out of the material.

Screens of different apertures and heights can be supplied to complement any development program. The diameter of spheroids produced is largely determined by the diameter of the extrudate.

The Extruder 20 has a simple operating structure and a small footprint to fit easily on the bench top. Product recovery (useful extrudate produced as a % of material added to the extruder) is very high and there are few dead spaces where material can collect. The achievable throughput is dependent on the properties of the material being extruded and the screen size used. The effective minimum load requirement is about 30g. Although the Extruder 20 is not designed as a production extruder for continuous use, some materials have been extruded at rates up to 25kg per hour.

Features

  • Bench top extruder for laboratory use.
  • Designed for experimental work using small quantities of product.
  • Standard screen 1mm aperture. Other sizes available.
  • All contact parts in 316 stainless steel, PTFE or HDPE.
  • Cabinet in 304 stainless steel.
  • Can be quickly dismantled for easy cleaning.
  • Easily fits in isolator for potent compounds.
  • Ideal extruder to use with the Caleva Multi Bowl Spheronizer.
  • Options

    There are a number of options available to suit your application. Feel free to call us so we can determine which options are suitable for you.

    The options available are:

    • Extrusion screens with holes from 0.5mm-3.0mm diameter.
    • Specialty screen configurations available.
    • Reduced height extrusion screen and roller assemblies.
    • Knurled rollers (may be helpful for certain types of compounds).
    • Data acquisition package.
    • Installation, start-up and training.
    • Product contact material certificates.
    • Power meter.
    • IQ OQ Document Package.

    Specs

    Loading: Manual, with feed tray positioned above inlet.
    Overall Dimensions (cm): 40x25x50
    Weight: 25 Kg
    Cabinet: Grained 304 SS
    Contact Parts: 316 SS, food-grade plastic, and Acrylic
    Controls: Front mounted panel with STOP/START buttons, POWER ON, MOTOR ON indicators. A built in tachometer shows extruder rotation speed. Speed is set by an infinitely variable potentiometer.
    Processing Capacity: Minimum load is about 30-50g. Output can be up to 25kg per hour, depending on characteristics of the material being extruded.
    Standard Extrusion Screen: 150mm diameter with holes 1mm diameter x 1mm deep, however, a wide range of screen hole sizes are available. Please contact us for details.
    Motor: 250W
    Utilities: Electric 115 VAC or to user requirements
    Documentation: Installation/Operation Manual
    Specifications may be subject to change without notice.

    Videos

    If you have trouble viewing the video clip in your browser, you can view or download (right click and “Save Link As” or “Save Target As”) the MP4 versions of the Caleva Benchtop Screen Extruder and Spheronizer video clip.

    Pictures

    Caleva Model 20 Extruder
    Caleva Model 20 Extruder
    Full height screen for Caleva Model 20 Extruder
    Full height screen for Caleva Model 20 Extruder
    Half height screen for Caleva Model 20 Extruder
    Half height screen for Caleva Model 20 Extruder
    Extruder 20 with data acquisition package
    Extruder 20 with data acquisition package
    Precision CNC machine drilled holes ensure high quality extrudate
    Precision CNC machine drilled holes ensure high quality extrudate
    General arrangement, Caleva Model 20 Extruder
    General arrangement, Caleva Model 20 Extruder"
    High quality extrudate from Caleva Model 20 Extruder
    High quality extrudate from Caleva Model 20 Extruder
    Tray of extrudate produced by Caleva Model 20 Extruder
    Tray of extrudate produced by Caleva Model 20 Extruder
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    The Caleva Model 20 Extruder

    The Caleva Model 20 Laboratory Extruder

    The Caleva Model 20 Benchtop Laboratory Extruder